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[Studies on the kinetics of methaqualone in the course of labour (author's transl)]
A 0,4 g (1598,06 mumol) dose of methaqualone was administered orally to 19 parturient at the beginning of the first stage of delivery. In comparison with former results, got from a control-group of nonpregnant and pregnant women in the last third of pregnancy, it was found a significantly prolonged biological half-life and a decrease of the fictitious initial concentration.
A 0,4 g (1598,06 mumol) dose of methaqualone was administered orally to 19 parturient at the beginning of the first stage of delivery. In comparison with former results, got from a control-group of nonpregnant and pregnant women in the last third of pregnancy, it was found a significantly prolonged biological half-life and a decrease of the fictitious initial concentration.