[Serum markers of B virus in chronic active hepatitis]

Serological B virus markers were determined by radioimmunoassay in 25 cases of chronic active hepatitis. One or more of these markers were identified in 13 out of 25 patients. Clinical correlation was made between the presence or absence of the markers. The marker most frequently encountered was anti hepatitis B Core antigen. In general those patients with hepatitis B surface antigen and hepatitis e antigen had a less favorable clinical course. Those patients who were serological negative to these markers showed frequent elevation of IgG.