Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Necrotizing enterocolitis (NEC) - pathogenesis and therapy (author's transl)]

P Schweizer, E Leidig, H Mentzel

    Zeitschrift Fur Kinderchirurgie : Organ Der Deutschen, Der Schweizerischen Und Der Osterreichischen Gesellschaft Fur Kinderchirurgie = Surgery in Infancy and Childhood
    |June 1, 1981
    PubMed
    Summary

    Necrotizing enterocolitis (NEC) in infants is strongly linked to intestinal ischemia. Early surgical intervention, between stage II and III, is crucial for better outcomes in NEC treatment.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Advancing Systemic Risk Assessment for Complex, Interdependent Systems: A Research Agenda.

    Risk analysis : an official publication of the Society for Risk Analysis·2026
    Same author

    Beaver effects on macroinvertebrate assemblages in two streams with contrasting morphology.

    The Science of the total environment·2020
    Same author

    Archives of gynecology and obstetrics·2016
    Same author

    cDNA cloning, in vitro transcription and partial sequence analysis of mRNAs from winter wheat (Triticum aestivum L.) with induced resistance to Erysiphe graminis f. sp. tritici.

    Plant molecular biology·2013
    Same author

    Differences in root functions during long-term drought adaptation: comparison of active gene sets of two wheat genotypes.

    Plant biology (Stuttgart, Germany)·2010
    Same author

    Immunohistochemical localization of nanog and Oct4 in stem cell compartments of human sacrococcygeal teratomas.

    Histopathology·2008

    Area of Science:

    • Pediatric Gastroenterology
    • Neonatal Surgery
    • Clinical Pathology

    Context:

    • Necrotizing enterocolitis (NEC) is a severe gastrointestinal condition affecting newborns.
    • Understanding NEC's etiology and optimal surgical timing is critical for infant survival.
    • This study examines 39 pediatric cases to clarify disease mechanisms and treatment indications.

    Purpose:

    • To investigate the pathogeny of necrotizing enterocolitis (NEC).
    • To determine the optimal timing for surgical intervention in NEC cases.
    • To correlate clinical findings with disease staging and outcomes.

    Summary:

    • Clinical and hematological data suggest intestinal ischemia is essential for NEC development.
    • Disseminated intravascular coagulation is unlikely to be the primary cause.

    Related Experiment Videos

  • A four-stage classification system for NEC is proposed, based on clinical presentation, platelet count, and serum sodium levels.
  • Surgical intervention is recommended at the transition from stage II to stage III, characterized by progressive bleeding, edema, thrombocytopenia, and hyponatremia.

    • Impact:

    • Provides a staging system to guide clinical management of NEC.
    • Identifies intestinal ischemia as a key factor in NEC pathogenesis.
    • Recommends specific timing for surgical intervention to improve NEC treatment outcomes.