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Published on: May 10, 2013
The measurement of creatinine: a comparison between the Beckman Creatinine Analyzer II and the Selective Analyzer GSA
Abstract:
The measurement of creatinine by two Jaffé-based procedures is described. In comparing the Beckman Creatinine Analyzer II and the Greiner Selective Analyzer GSA IID, better between-day precision was observed with the former. Percentage recovery of creatinine added to serum was quantitative for the Beckman Creatinine Analyzer II and 92-95% for the Greiner Selective Analyzer. The Greiner Selective Analyzer employs a serum blank and for this reason interference produced by pseudo-Jaffé chromogens in the measurement of creatinine was far less significant than the corresponding interferences observed with the Beckman Creatinine Analyzer II. Comparison of results obtained on 100 sera and 40 urine samples provided correlation coefficients of 0.998 and 0.997 respectively.
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