Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The eleventh nerve in radical neck surgery

J H Brandenburg, C Y Lee

    The Laryngoscope
    |November 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Preserving the spinal accessory nerve during radical neck dissection significantly reduces tumor recurrence rates. This modification to the classical procedure improves outcomes without compromising cancer cure rates.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Effect of hyperthermia on intracellular pH in human U-87 MG glioblastoma cells.

    Oncology·1995
    Same author

    Purified rat acid-labile subunit and recombinant human insulin-like growth factor (IGF)-binding protein-3 can form a 150-kilodalton binary complex in vitro in the absence of IGFs.

    Endocrinology·1995
    Same author

    Molecular analysis of an extracellular protease gene from Vibrio parahaemolyticus.

    Microbiology (Reading, England)·1995
    Same author

    Set-shifting aptitude in Parkinson's disease: external versus internal cues.

    Psychological reports·1995
    Same author

    Luminal epidermal growth factor is trophic to the small intestine of parenterally fed rats.

    Clinical science (London, England : 1979)·1995
    Same author

    Comparative mathematical analyses of freezing in lung and solid tissue.

    Cryobiology·1995

    Area of Science:

    • Head and Neck Surgery
    • Surgical Oncology

    Background:

    • Radical neck dissection (RND) is a standard treatment for head and neck cancers.
    • Sacrifice of the spinal accessory nerve (SAN) during RND leads to significant morbidity, notably shoulder syndrome.
    • Preserving the SAN during RND is controversial due to concerns about oncological control.

    Purpose of the Study:

    • To evaluate the impact of spinal accessory nerve preservation on tumor recurrence rates in radical neck dissections.
    • To determine if sparing the SAN compromises oncological outcomes in elective and therapeutic neck dissections.

    Main Methods:

    • Retrospective analysis of 370 radical neck dissections performed between 1970 and 1978.
    • Comparison of tumor recurrence rates between cases where the SAN was resected versus preserved.

    Related Experiment Videos

  • Data collected from the University of Wisconsin Clinical Science Center and Wisconsin Head and Neck Cancer Control Network Hospitals.

    • Main Results:

    • The overall recurrence rate for classical RND was 12%.
    • When the spinal accessory nerve was spared, the neck recurrence rate decreased to 6%.
    • No compromise in cure rates was observed when the SAN was preserved in elective and selected therapeutic neck dissections.

    Conclusions:

    • Modification of the classical radical neck dissection to preserve the spinal accessory nerve is oncologically safe.
    • Sparing the SAN can be achieved without jeopardizing cure rates in elective and selected therapeutic neck dissections.
    • This approach can reduce patient morbidity associated with shoulder syndrome.