Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Developing guidelines for working with antineoplastic drugs

American Journal of Hospital Pharmacy

|November 1, 1981

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Phase I dose escalation study of topotecan combined with alternating schedules of paclitaxel and carboplatin in advanced solid tumors.

Annals of oncology : official journal of the European Society for Medical Oncology·2001

Same author

Induction paclitaxel and carboplatin for patients with head and neck carcinoma. Analysis of 62 patients treated between 1994 an 1999.

Cancer·2001

Same author

Exposure to hazardous drugs: time to reevaluate your program?

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists·1999

Same author

Cimetidine therapy for recalcitrant warts in adults: is it any better than placebo?

Journal of the American Academy of Dermatology·1999

Same author

Ototoxicity associated with vinblastine.

The Annals of pharmacotherapy·1999

Same author

A phase II evaluation of pentoxifylline combined with radiation in the treatment of brain metastases.

International journal of oncology·1998

Same journal

National health care reform, Part 2: Response to pharmacists.

American journal of hospital pharmacy·1994

Same journal

Validity of originality assessment.

American journal of hospital pharmacy·1994

Same journal

Unit dose dispensing of chromic phosphate P 32 suspension.

American journal of hospital pharmacy·1994

Same journal

Hydralazine injection still available.

American journal of hospital pharmacy·1994

Same journal

Improved extemporaneous formulation of cyclosporine ophthalmic drops.

American journal of hospital pharmacy·1994

Same journal

Paclitaxel diluent and the case of the slippery spike.

American journal of hospital pharmacy·1994

See all related articles

Antineoplastic drugs pose hazards during admixture and administration. Proper handling guidelines are crucial to protect healthcare workers from exposure to these potential carcinogens.

Area of Science:

Oncology
Occupational Health
Pharmacology

Background:

Injectable antineoplastic drugs present significant occupational hazards.
Concerns exist regarding the safe admixture and administration of these potent agents.
Potential mutagenicity and carcinogenicity of anticancer drugs require careful consideration.

Purpose of the Study:

To review the hazardous properties of antineoplastic drugs.
To discuss problems associated with their preparation and administration.
To suggest guidelines for safe handling to protect healthcare workers.

Main Methods:

Literature review of antineoplastic drug hazards.
Discussion of mutagenicity and carcinogenicity data.
Examination of federal regulations concerning carcinogens.

Related Experiment Videos

Main Results:

Antineoplastic agents exhibit mutagenic and carcinogenic potential.
Existing literature highlights concerns regarding handling practices.
Federal regulations address carcinogen control.

Conclusions:

Healthcare workers face risks from exposure to antineoplastic drugs.
Proper handling protocols are essential to minimize occupational exposure.
Hospitals must implement robust guidelines for managing antineoplastic drug products.