Red cell preservation and removal system of purine derivatives
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Updated: Oct 4, 2026

Antigens Protected Functional Red Blood Cells By The Membrane Grafting Of Compact Hyperbranched Polyglycerols
Published on: January 2, 2013
Abstract:
The new preservative containing high concentrations of adenine (8 mM), inosine (40 mM) and other chemicals which was indicated by Nakao et al., was applied to the preservation of red cell concentrates. Moreover, the system for the removal of purine derivatives (adenine, inosine and hypoxanthine) added and produced in stored samples was developed, using bead activated charcoal coated with the blood-compatible polymer (Hydron). Over 90% of purine derivatives in the medium and erythrocytes were removed by Hydron-coated bead activated charcoal (HAC) column. The recovery of erythrocytes by HAC column treatment was over 98%.
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