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[Does linear psoriasis exist? (author's transl)]

C Goujon, A M Pierini, J Thivolet

    Annales De Dermatologie Et De Venereologie
    |January 1, 1981
    PubMed
    Summary
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    A congenital nevus can trigger psoriasis development, illustrating the Köbner phenomenon. Treatment with Ro 10.9359 resolved both conditions, suggesting epidermal nevi are sites for psoriatic lesions.

    Area of Science:

    • Dermatology
    • Pathology

    Background:

    • Psoriasis is a chronic inflammatory skin condition.
    • Congenital nevi are benign skin growths present from birth.
    • The Köbner phenomenon describes lesion development at trauma sites.

    Observation:

    • A child presented with congenital nevus unius lateris and new-onset linear psoriasis localized to the nevus.
    • Histology confirmed psoriasis and epidermolytic hyperkeratosis in the lesion overlying the nevus.
    • The patient also had generalized psoriatic lesions.

    Findings:

    • Psoriasis overlying an epidermal nevus is a manifestation of the Köbner phenomenon.
    • Treatment with Ro 10.9359 led to the resolution of both the nevus and psoriasis.
    • Literature review identified five similar cases, supporting the epidermal nevus as a site for psoriatic lesions.

    Related Experiment Videos

  • Linear psoriasis may not be a distinct entity but rather inflammatory linear verrucous epidermal nevus (ILVEN).

    • Implications:

    • Epidermal nevi can act as a nidus for psoriasis development in susceptible individuals.
    • A broader definition of the Köbner phenomenon may be warranted.
    • Findings challenge the classification of linear psoriasis, suggesting it is often ILVEN.