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Vitelliform macular dystrophy of late onset
The British Journal of Ophthalmology
|December 1, 1981
Summary
Vitelliform macular dystrophy can present atypically late in life, with symptoms appearing in the fifth decade. Elderly patients may exhibit signs similar to age-related macular degeneration.
Area of Science:
- Ophthalmology
- Medical Genetics
Background:
- Vitelliform macular dystrophy (VMD) is a group of inherited retinal diseases.
- Typically, VMD manifests symptoms in the first or second decade of life.
Observation:
- This report details a family with VMD where the proband presented symptoms at age 51.
- This represents a significantly later onset than typically observed.
Findings:
- Late-onset VMD in the proband.
- Clinical presentation in elderly patients can mimic age-related degenerative choroidopathy of the macula.
Implications:
- Highlights the potential for delayed diagnosis in VMD.
- Suggests considering VMD in the differential diagnosis of macular changes in elderly individuals.
- Underscores the phenotypic variability of inherited retinal disorders.
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