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Bilateral multifocal retinal arteriolar sheathing as the only ocular finding in hereditary amyloidosis
1Department of Ophthalmology, New York University Medical Center, NY 10016, USA.
Purpose:
To report the early ocular findings in hereditary amyloidosis.
Methods:
Case report of a visually asymptomatic, 52-year-old Mexican man with systemic manifestations of amyloidosis (peripheral neuropathy, restrictive cardiomyopathy), with a positive family history, and with amyloid on an endomyocardial biopsy specimen, who had bilateral multifocal sheathing or cuffing of the peripheral retinal arterioles.
Result:
An extensive evaluation for retinal vasculitis was discontinued when hereditary amyloidosis was diagnosed.
Conclusion:
Focal retinal periarteriolar plaques of amyloid may be the earliest and only ocular finding of hereditary amyloidosis.

