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Updated: Aug 14, 2026

Transretinal ERG Recordings from Mouse Retina: Rod and Cone Photoresponses
Published on: March 14, 2012
Autosomal dominant congenital stationary night blindness and normal fundus with an electronegative electroretinogram
K G Noble1, R E Carr, I M Siegel
1Department of Ophthalmology, New York University Medical Center, NY 10016.
Abstract:
We studied three members of three successive generations of a family with autosomal dominant congenital stationary night blindness and normal fundi. Psychophysical studies on two members showed normal final cone thresholds and mildly increased rod thresholds. Full-field electroretinograms on all three members showed normal photopic b-wave amplitudes and implicit times. Under scotopic conditions, the rod response was absent, and with a bright flash stimulus, there was a normal a-wave with no b-wave. This electronegative dark-adapted electroretinogram resembled the Schubert-Bornschein type seen in congenital stationary blindness, which has been seen only in autosomal and X-linked recessive pedigrees.
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