Related Experiment Video

Updated: Aug 19, 2026

Introduction to Solid Supported Membrane Based Electrophysiology
19:56

Introduction to Solid Supported Membrane Based Electrophysiology

Published on: May 11, 2013

Kinetic analysis of a family of cotransport models

R J Turner

    Biochimica Et Biophysica Acta
    |December 7, 1981
    PubMed

    More Related Videos

    Models and Methods to Evaluate Transport of Drug Delivery Systems Across Cellular Barriers18:57

    Models and Methods to Evaluate Transport of Drug Delivery Systems Across Cellular Barriers

    Published on: October 17, 2013

    Characterizing the Composition of Molecular Motors on Moving Axonal Cargo Using "Cargo Mapping" Analysis11:09

    Characterizing the Composition of Molecular Motors on Moving Axonal Cargo Using "Cargo Mapping" Analysis

    Published on: October 30, 2014

    Related Concept Videos

    Pharmacokinetic Models: Overview01:20

    Pharmacokinetic Models: Overview

    Pharmacokinetic models utilize mathematical analysis to achieve a detailed quantitative understanding of a drug's life cycle within the body. They are instrumental in simulating a drug's pharmacokinetic parameters, predicting drug concentrations over time, optimizing dosage regimens, linking concentrations with pharmacologic activity, and estimating potential toxicity.
    There are three primary types of models: empirical, compartment, and physiological. Empirical models, with minimal assumptions,...
    Model Approaches for Pharmacokinetic Data: Compartment Models01:14

    Model Approaches for Pharmacokinetic Data: Compartment Models

    Compartmental analysis is a widely adopted approach to characterizing drug pharmacokinetics. It uses compartment models that conceptualize the body as a collection of reversibly communicating compartments, each representing a group of tissues exhibiting similar drug distribution characteristics. The movement rate of the drug between these compartments is typically described by first-order kinetics.
    Two primary types of compartment models are recognized: mammillary and catenary. The more...
    Two-Compartment Open Model: Overview01:05

    Two-Compartment Open Model: Overview

    Multicompartmental models are crucial tools in pharmacokinetics, providing a framework to understand how drugs move within the body. The two-compartment model is a crucial subtype, segmenting the body into central and peripheral compartments. The central compartment represents areas with high blood flow, such as plasma and highly perfused organs like the kidneys and liver, while the peripheral compartment signifies tissues with lower blood flow, like adipose tissue and muscle tissue.
    The...
    Mechanistic Models: Overview of Compartment Models01:21

    Mechanistic Models: Overview of Compartment Models

    Mechanistic models, a category encompassing both physiological and compartmental modeling, differ from empirical models' approaches to incorporating known factors about the systems being modeled. Empirical models describe data with minimal assumptions, while mechanistic models aim to provide a robust description of available data by specifying assumptions and integrating known factors about the system. Compartmental analysis is a key example of a mechanistic model in pharmacokinetics and...
    Mechanistic Models: Compartment Models in Individual and Population Analysis01:23

    Mechanistic Models: Compartment Models in Individual and Population Analysis

    Mechanistic models are utilized in individual analysis using single-source data, but imperfections arise due to data collection errors, preventing perfect prediction of observed data. The mathematical equation involves known values (Xi), observed concentrations (Ci), measurement errors (εi), model parameters (ϕj), and the related function (ƒi) for i number of values. Different least-squares metrics quantify differences between predicted and observed values. The ordinary least squares (OLS)...
    Pharmacokinetic Models: Comparison and Selection Criterion01:26

    Pharmacokinetic Models: Comparison and Selection Criterion

    Physiological and compartmental models are valuable tools used in studying biological systems. These models rely on differential equations to maintain mass balance within the system, ensuring an accurate representation of the dynamic processes at play.
    Physiological models take a detailed approach by considering specific molecular processes. They can predict drug distribution, metabolism, and elimination changes, providing a comprehensive understanding of how drugs interact with the body.