[Model studies of the effect of structural changes in cleaving embryo on electrical parameters of cellular...

Two models of the embryo developing from one initial cell by cleavage division are considered. Equivalent electrical schemes were constructed, changes in electrical coupling coefficient (Kec) and input resistance (ri) of the embryos during cleavage were estimated. Considerable influence of cleavage-related changes of membrane parameters on Kec and ri appears at the first five--ten cleavages and essentially depends on the ratio of contact and incontact membrane resistances. A comparison of the estimated curves of Kec and ri with experimental ones (loach and axolotl embryos) has shown that the model curves with the ratio rm/rc equalling 100 and 1000 are very close to the real ones.