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Perinatal listeriosis

G F Vawter

    Perspectives in Pediatric Pathology
    |January 1, 1981
    PubMed
    Summary

    Perinatal listeriosis, a serious infection in newborns, can lead to gestational loss and is associated with birth canal abnormalities. Early detection and understanding of its varied presentations are crucial for improved outcomes.

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    Area of Science:

    • Perinatology
    • Infectious Diseases
    • Neonatology

    Background:

    • Listerial infection in perinate (newborn) populations presents a broad spectrum of disease.
    • This includes intrauterine septicemia, amniotic infection syndrome, intrapartum infection, and postnatal infection.

    Purpose of the Study:

    • To analyze the spectrum and associations of perinatal listeriosis.
    • To highlight the potential for gestational loss and identify associated risk factors.

    Main Methods:

    • Review of clinical cases of listerial infection in perinate populations.
    • Analysis of disease presentation, including intrauterine, intrapartum, and postnatal infections.
    • Correlation of perinatal listeriosis with birth canal abnormalities and underlying maternal factors.

    Main Results:

    • Amniotic infection can result in gestational loss, with or without invasive bacteremia and septicemia.
    • Perinatal listeriosis is associated with birth canal abnormalities, mixed infections, and potential underlying metabolic or humoral abnormalities.
    • Morphologic findings are often non-specific, frequently complicated by secondary conditions like disseminated intravascular coagulopathy and circulatory compromise.

    Conclusions:

    • Perinatal listeriosis encompasses a wide range of clinical and pathological manifestations.
    • Associations with birth canal abnormalities and potential maternal factors warrant further investigation.
    • Recognizing the varied presentations is key to managing this serious neonatal infection.

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