Related Experiment Video

Updated: Aug 16, 2026

Measuring Bacterial Load and Immune Responses in Mice Infected with Listeria monocytogenes
12:50

Measuring Bacterial Load and Immune Responses in Mice Infected with Listeria monocytogenes

Published on: August 9, 2011

Perinatal listeriosis

G F Vawter

    Perspectives in Pediatric Pathology
    |January 1, 1981
    PubMed

    Insights

    Perinatal listeriosis, a serious infection in newborns, can lead to gestational loss and is associated with birth canal abnormalities. Early detection and understanding of its varied presentations are crucial for improved outcomes.

    Area of Science:

    • Perinatology
    • Infectious Diseases
    • Neonatology

    Background:

    • Listerial infection in perinate (newborn) populations presents a broad spectrum of disease.
    • This includes intrauterine septicemia, amniotic infection syndrome, intrapartum infection, and postnatal infection.

    Purpose of the Study:

    • To analyze the spectrum and associations of perinatal listeriosis.
    • To highlight the potential for gestational loss and identify associated risk factors.

    Main Methods:

    • Review of clinical cases of listerial infection in perinate populations.
    • Analysis of disease presentation, including intrauterine, intrapartum, and postnatal infections.
    • Correlation of perinatal listeriosis with birth canal abnormalities and underlying maternal factors.

    Main Results:

    • Amniotic infection can result in gestational loss, with or without invasive bacteremia and septicemia.
    • Perinatal listeriosis is associated with birth canal abnormalities, mixed infections, and potential underlying metabolic or humoral abnormalities.
    • Morphologic findings are often non-specific, frequently complicated by secondary conditions like disseminated intravascular coagulopathy and circulatory compromise.

    Conclusions:

    • Perinatal listeriosis encompasses a wide range of clinical and pathological manifestations.
    • Associations with birth canal abnormalities and potential maternal factors warrant further investigation.
    • Recognizing the varied presentations is key to managing this serious neonatal infection.

    More Related Videos

    Oral Transmission of Listeria monocytogenes in Mice via Ingestion of Contaminated Food08:38

    Oral Transmission of Listeria monocytogenes in Mice via Ingestion of Contaminated Food

    Published on: May 6, 2013

    Listeria monocytogenes Infection of the Brain05:02

    Listeria monocytogenes Infection of the Brain

    Published on: October 2, 2018

    Related Concept Videos

    Development of Human Microbiota01:30

    Development of Human Microbiota

    The human microbiota begins developing at birth and undergoes continual change as we age. Infancy marks a critical period of microbial sensitivity, offering a “window of opportunity” during which beneficial microbes help mature the immune system. By age three, children typically develop a more stable and diverse microbial community. Newborns acquire microbes from their immediate environment; vaginal delivery favors maternal vaginal microbes, while cesarean births favor microbes from the skin...
    Development of the Oral Microbiota01:28

    Development of the Oral Microbiota

    The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
    Bacterial Meningitis01:24

    Bacterial Meningitis

    Bacterial meningitis is a severe infectious disease involving inflammation of the meninges, the protective membranes surrounding the brain and spinal cord. It occurs when pathogenic bacteria cross the blood–brain barrier and enter the cerebrospinal fluid. Common causative organisms include Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae type b, Listeria monocytogenes, and Escherichia coli K1. The exact route of entry varies by pathogen and host condition.Routes of Entry...
    Viral Meningitis01:18

    Viral Meningitis

    Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
    Bacterial Meningitis I: Introduction01:22

    Bacterial Meningitis I: Introduction

    Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
    Bacterial Meningitis II: Pathophysiology01:26

    Bacterial Meningitis II: Pathophysiology

    Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...