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[Pinkus' trichodiscoma (author's transl)]

E Grosshans, T Dungler, D Hanau

Annales De Dermatologie Et De Venereologie

|January 1, 1981

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Trichodiscomas are benign skin tumors originating from hair disk structures. This study details their histological features, noting a lack of Merkel cells and increased vascularity, suggesting a dermal origin.

Area of Science:

Dermatopathology
Dermatology
Oncology

Background:

Trichodiscoma, a rare cutaneous tumor, originates from the human retropilar hair disk.
These lesions are often multiple, occurring in adults, and associated with perifollicular fibromas and acrochordons.
Previous understanding suggested limited clinical presentations, potentially underestimating prevalence.

Observation:

Two female patients (39 and 47 years old) presented with multiple trichodiscomas.
The first patient had seven tumors in a linear pattern on the scalp.
The second patient exhibited disseminated lesions across her chest.

Findings:

Histological examination revealed a paucity of Merkel cells in the epidermis.
Hyperplasia of capillary blood vessels and their endothelial cells was noted.

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Thick myelinated nerve fibers were present deep within the lesion, not near the epidermis.

Proliferation of loose dermal connective tissue and sparse, marginally located hair follicles were observed.

Electron microscopy confirmed these features in one case.

Implications:

Trichodiscoma appears to arise from a hyperplasia of dermal components of the hair disk.
Merkel cells, while part of the normal hair disk, are not involved in trichodiscoma formation.
The findings support the potential identification of patients with paucilesional (few lesions) trichodiscoma, as suggested by Pinkus.
This research refines the understanding of trichodiscoma histogenesis and clinical presentation.