Chronic aflatoxicosis in cattle

Pathological, hematological and plasma enzymatic studies were made on milk cattle affected by chronic aflatoxicosis caused by the prolonged feeding of concentrate feed mixtures containing contaminated groundnut cake having aflatoxin B1 (110 ug/kg groundnut cake at the time of sampling), B2, G1 and G2. Clinical and necropsy observations on liver included proliferation of connective tissue along portal triads leaving small group of hepatocytes intact. Liver function tests showed liver damage in three of the four affected animals studied.