Related Experiment Video
Updated: Aug 10, 2026

Experimental and Imaging Techniques for Examining Fibrin Clot Structures in Normal and Diseased States
Published on: April 1, 2015
Changes of platelet phospholipids in diabetes mellitus
Abstract:
In the present study the phospholipid and fatty acid concentration of platelet has been measured in patients with poorly and well controlled diabetes mellitus and in control subjects. An increased phosphatidylethanolamine (p less than 0.01) and phosphatidylserine (p less than 0.001) content of platelets was found in poorly controlled diabetes as well as an increased phosphatidylserine (p less then 0.001) concentration in well controlled diabetes. The most notable changes of platelet fatty acids were a decreased concentration of palmitic (16:0; p less than 0.01) and linoleic acid (18:2; p less than 0.001) in the poorly controlled diabetes as well as (p less than 0.001) and (p less than 0.025) in the well controlled diabetes, respectively. Also, an increased concentration of arachidonic acid (20:4; p less than 0.001) was found in both groups of diabetics. No differences were found in phospholipid concentration between patients with and without vascular diseases.
More Related Videos
Related Concept Videos
Phosphoinositides and PIPs
Different phosphoinositides are synthesized and recruited on the cytosolic face of the plasma membrane. The localization of specific phosphoinositides concentrated in separate membrane...
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...
Blood Studies for Cardiovascular System III: Serum Lipid Profile
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
Peripheral Artery Disease I: Introduction
Type II Diabetes II: Pathophysiology
Diabetic Retinopathy

