Prostaglandin E1 fever in the crayfish Cambarus bartoni

Groups of 10 crayfish were injected with prostaglandin E1, at 1 of 3 pharmacological doses (0.5, 0.1 or 0.05 mg), into the haemocoel, and individually allowed to thermoregulate in electronic shuttleboxes for 24 hr. The mean preferred temperature of each group was then compared with their mean preferred temperature for 24 hr prior to injection, and with the mean preferred temperature of 10 crayfish injected with pyrogen-free saline. Dosage-dependent increases in preferred temperature were observed in the crayfish injected with PGE1, ranging from 1 degrees C at the lowest dosage to 3,4 degrees C at the highest dosage, above the normal thermal preferendum for this species of 22.1 degrees C.