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Eosinophilic gastroenteritis and ascites

W A Harmon, C A Helman

    Journal of Clinical Gastroenterology
    |December 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Eosinophilic gastroenteritis with ascites is a rare condition. Corticosteroid therapy effectively resolved gastrointestinal symptoms and ascites in a patient with this diagnosis.

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    Area of Science:

    • Gastroenterology
    • Internal Medicine
    • Allergy and Immunology

    Background:

    • Eosinophilic gastroenteritis (EG) is a rare disorder characterized by eosinophilic infiltration of the gastrointestinal tract.
    • Ascites, a less common manifestation of EG, presents diagnostic challenges.

    Observation:

    • A 53-year-old man presented with massive abdominal swelling, epigastric pain, and a history of atopy.
    • Laboratory findings revealed peripheral eosinophilia (4420/mm3) and exudative ascites with 99% eosinophils.

    Findings:

    • Endoscopic, contrast X-ray, and small bowel biopsy findings were compatible with eosinophilic gastroenteritis with ascites.
    • Comparison with 14 previously reported cases highlights the rarity and clinical presentation of this condition.

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    Implications:

    • Corticosteroid therapy led to complete resolution of gastrointestinal symptoms and ascites within 4 weeks.
    • This case underscores the importance of considering EG in patients with unexplained ascites and eosinophilia.
    • Effective management with corticosteroids suggests a favorable prognosis with appropriate treatment.