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Updated: Aug 6, 2026

Stereotaxic Surgery for Excitotoxic Lesion of Specific Brain Areas in the Adult Rat
Published on: July 19, 2012
[Effect of DL-allyglycine on amygdala kindling in the rat (author's transl)]
Abstract:
The effect of decreased cerebral GABA levels on the development of amygdaloid kindling in rats was investigated. DL-Allylglycine, an inhibitor of glutamic acid decarboxylase (GAD), administered for 2 or 9 days (100 mg/kg and 50 mg/kg respectively) was found to accelerate the kindling process. The results are discussed according to a possible role of GABA mechanisms in the kindling phenomenon.
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