[Intrahepatic cholangiodysplasia in 2 brothers. Concept of the entity]

The histopathologic aspects of the intrahepatic dysplasic bile ducts (cholangiodysplasia) found in two brothers, one of them asymptomatic, are discussed. This entity is characterized by interlobular bile ducts proliferation and portal fibrosis, without cholestasis but with chronic active cholangitis. The differential diagnosis and the probable genesis of the cholangiodysplasias are discussed.