[Normal values of serum IgD in children depending on their age]

In the Institute of Mother and Child in Warsaw there were determined normal values of IgG, IgA, IgM and IgE for different ages of children and youth. The determination of normal IgD levels is the last stage in this kind of studies concerning immunoglobulins. IgD levels were estimated in 372 cases in 19 age groups: in the cord sera, infant sera and older healthy children as well as in healthy adults sera. The IgD concentration was determined by Mancini method and given in I.U/ml. The results were statistically analysed. In all samples of cord sera no IgD traces were found. In infant sera (up to one year) IgD level is very low and was detected in 27% of cases. The percentage of detectability as well as the mean IgD concentration in serum grows systematically to the age of 15 years. There is high statistically significant correlation between serum IgD concentration and the age both for the arithmetical means (r = 0,33) and for geometrical values (r = 0,39). The correlation coefficients between detectability of serum IgD and age are higher (linear dependence-r = 0,67, square dependence - r = 0,75).