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Breast examination does not elevate serum prolactin

J Jarrell, S Franks, R McInnes

    Fertility and Sterility
    |January 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

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    Physical exams did not alter serum prolactin or cortisol levels in infertility patients. This suggests stress from examinations may not significantly impact these hormone levels in this group.

    Area of Science:

    • Endocrinology
    • Reproductive Medicine
    • Clinical Physiology

    Background:

    • Elevated serum prolactin is associated with infertility.
    • Physical examinations, including pelvic exams, may induce stress.
    • Stress can influence hormone levels like prolactin and cortisol.

    Purpose of the Study:

    • To investigate the effect of physical examinations on serum prolactin and cortisol levels in patients presenting to an infertility clinic.
    • To determine if examination-induced stress impacts hormone levels in infertile patients.

    Main Methods:

    • Serum prolactin and cortisol were measured in 24 patients before and after a comprehensive physical examination.
    • The examination included pelvic assessment and breast examination for galactorrhea.

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  • Patients were stratified based on basal prolactin values (normal vs. high).

    • Main Results:

    • No statistically significant changes in serum prolactin or cortisol levels were observed post-examination in the overall group.
    • Hormone levels remained unchanged in patients with normal basal prolactin and those with high basal prolactin.
    • The study found no significant impact of the physical examination on these hormone levels (P < 0.05).

    Conclusions:

    • Thorough physical examinations, including pelvic exams, do not appear to significantly alter serum prolactin or cortisol levels in patients attending an infertility center.
    • The findings suggest that stress associated with these examinations may not be a primary driver of occasional elevations in basal prolactin values.
    • Further research could explore other factors contributing to elevated prolactin in infertile patients.