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Updated: Aug 18, 2026

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Severe Burn Injury in a Swine Model for Clinical Dressing Assessment
Published on: November 6, 2018
Burn wound sepsis: effect of delayed treatment with topical chemotherapy on survival
The Journal of Trauma
|February 1, 1980
Abstract:
Using a standardized laboratory rat model of burn wound sepsis, a regimen of once a day application of Silvadene has been found to be more effective treatment than Sulfamylon or cerium-Silvadene. Delaying treatment following infection resulted in decreased survival. Possible reasons for difference in mortality are once-daily application, or perhaps a change in sensitivity between drugs and the infective organism (Ps. aeruginosa) over time.
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