Related Experiment Video
Updated: Oct 7, 2026

The CYP2D6 Animal Model: How to Induce Autoimmune Hepatitis in Mice
Published on: February 3, 2012
Asymptomatic primary biliary cirrhosis
Abstract:
Ten asymptomatic patients with biochemical, immunologic, and histologic features of primary biliary cirrhosis are described. Their liver disease was first suggested by an elevated alkaline phosphatase level upon routine biochemical screening tests. Increasing awareness of this disease has led to its increased detection in asymptomatic patients. It is this group of asymptomatic patients from whom we will learn more about the natural history of primary biliary cirrhosis.
Related Concept Videos
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Diseases of the Liver and Gallbladder
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not related to...
Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Cirrhosis I: Introduction
Chronic Pancreatitis I: Introduction
Chronic Pancreatitis II: Pathophysiology

