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Eosinophilic gastroenteritis

A Schulman, P C Morton, B E Dietrich

    Clinical Radiology
    |January 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Eosinophilic gastroenteritis is a rare condition causing eosinophil infiltration in the stomach and small bowel walls. Radiologic findings of thickened folds and walls, along with clinical symptoms, aid diagnosis, often responding to corticosteroid therapy.

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    Area of Science:

    • Gastroenterology
    • Radiology
    • Pathology

    Background:

    • Eosinophilic gastroenteritis (EGE) is characterized by eosinophilic infiltration of the gastrointestinal tract.
    • Diagnosis can be challenging due to potential mucosal sparing and reliance on invasive biopsies.

    Observation:

    • Radiologically, EGE presents as small bowel wall and circular fold thickening without mucosal ulceration.
    • Clinical features include abdominal cramps, diarrhea, distension, nausea, and vomiting, often with a history of allergic disorders.
    • Two presented cases showed no gastric involvement or peripheral blood eosinophilia, diverging from typical presentations.

    Findings:

    • Radiological findings of thickened small bowel folds and walls are key indicators.
    • Clinical presentation combined with radiological evidence can suggest EGE.

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  • Corticosteroid therapy demonstrates rapid improvement in clinical and radiological signs.

    • Implications:

    • Radiologists should consider EGE in the differential diagnosis for unexplained small bowel thickening, especially with compatible clinical history.
    • Non-invasive diagnostic approaches, including clinical-radiological correlation and therapeutic trials, can be effective.
    • Further research may clarify atypical presentations of EGE, such as absent gastric involvement or peripheral eosinophilia.