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Related Experiment Videos

Primary cutaneous histoplasmosis: a new presentation

M Giessel, J M Rau

    Cutis
    |February 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    A rare skin manifestation of histoplasmosis mimicked cellulitis in an immunocompromised patient. This case highlights an unusual presentation of a fungal infection, differing from previously documented forms.

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    Area of Science:

    • Dermatology
    • Infectious Diseases
    • Mycology

    Background:

    • Chronic steroid therapy can predispose individuals to opportunistic infections.
    • Histoplasmosis is a fungal infection typically affecting the lungs, but can manifest cutaneously.
    • Cutaneous histoplasmosis presentations vary, often appearing as nodular or ulcerative lesions.

    Observation:

    • A 51-year-old male on long-term corticosteroids developed a skin eruption resembling cellulitis or erysipelas.
    • The patient had no signs of systemic histoplasmosis involvement.
    • This clinical presentation is atypical for previously reported cases of cutaneous histoplasmosis.

    Findings:

    • Histopathological examination confirmed the eruption to be histoplasmosis.
    • The patient's presentation differed significantly from the two nodular and three noduloulcerative cases previously documented.

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  • The lesion was not self-limited or minimally tender, unlike prior reports.

    • Implications:

    • This case expands the spectrum of clinical presentations for cutaneous histoplasmosis.
    • Physicians should consider histoplasmosis in the differential diagnosis of atypical skin lesions, especially in immunocompromised patients.
    • Early recognition and diagnosis are crucial for appropriate management of this fungal infection.