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Retrospective analysis of a modified Goeckerman regimen for the treatment of psoriasis
Abstract:
The records of all patients treated at Mount Sinai Medical Center of Greater Miami with a modified Goeckerman regimen from 1972 to 1977 were analyzed. When a stringent definition of "clearing" was applied, it was found that approximately half of the patients were cleared of their psoriasis on this regimen and that the time the patients remained clear following treatment averaged 125 days. The mean number of treatments required for clearing was twenty-four which is in the same range as reported for PUVA therapy. For those patients that cleared, this average number of treatments was a more important variable than the time over which the treatments were administered.
Insights
The modified Goeckerman regimen effectively cleared psoriasis in about half of patients, keeping them clear for an average of 125 days. The number of treatments was more critical for clearing than treatment duration.
Area of Science:
- Dermatology
- Phototherapy
- Psoriasis Treatment
Background:
- Psoriasis is a chronic skin condition requiring effective treatment.
- The modified Goeckerman regimen has been used for psoriasis management.
Purpose of the Study:
- To evaluate the efficacy of the modified Goeckerman regimen for psoriasis treatment.
- To determine patient outcomes, including clearing rates and duration of remission.
Main Methods:
- Retrospective analysis of patient records treated between 1972 and 1977.
- Application of a stringent definition for 'clearing' of psoriasis.
- Analysis of treatment frequency and duration.
Main Results:
- Approximately 50% of patients achieved clearing of psoriasis.
- Patients remained clear for an average of 125 days post-treatment.
- Mean of 24 treatments required for clearing, comparable to PUVA therapy.
Conclusions:
- The modified Goeckerman regimen is an effective psoriasis treatment option.
- Number of treatments is a key factor for achieving remission.
- This regimen offers a comparable alternative to PUVA therapy in terms of treatment frequency.