Related Experiment Video
Updated: Jul 3, 2026

Killer Artificial Antigen Presenting Cells (KaAPC) for Efficient In Vitro Depletion of Human Antigen-specific T Cells
Published on: August 12, 2014
Kawasaki disease in healthy young adult
Insights
Kawasaki disease, a rare illness in adults, was diagnosed in a 26-year-old woman. This case highlights the importance of recognizing mucocutaneous lymph node syndrome in adult patients.
Area of Science:
- Pediatrics
- Rheumatology
- Infectious Diseases
Background:
- Kawasaki disease (KD), also known as mucocutaneous lymph node syndrome, is an acute febrile illness predominantly affecting young children.
- Diagnosis typically requires fever lasting ≥5 days plus specific clinical criteria, excluding other known causes.
Observation:
- This report details a 26-year-old woman who met the diagnostic criteria for Kawasaki disease.
- The patient presented with prolonged fever and characteristic symptoms including conjunctival injection, mucous membrane involvement, extremity changes, rash, and lymphadenopathy.
Findings:
- The adult patient fulfilled the standard diagnostic criteria for Kawasaki disease, despite its rarity in this age group.
- The clinical presentation included key features such as fever, conjunctivitis, oral mucosal changes, extremity edema/desquamation, rash, and cervical lymphadenopathy.
Implications:
- This case underscores the necessity of considering Kawasaki disease in the differential diagnosis of febrile illnesses in adults presenting with compatible symptoms.
- Recognizing KD in adults is crucial for timely treatment and preventing potential cardiac complications, such as coronary artery aneurysms.
- Further research may be warranted to understand the epidemiology and clinical variations of Kawasaki disease in adult populations.
Abstract:
This report describes a 26-year-old woman who fulfills the criteria for the diagnosis of Kawasaki disease or mucocutaneous lymph node syndrome, an acute febrile illness that usually afflicts young children. The diagnosis is made in persons with fever lasting 5 or more days when four of the following criteria are met: bilateral injection of ocular conjunctivae; the involvement of the mucous membranes of the upper respiratory tract consisting of any combination of the following--redness and fissuring of lips; "strawberry tongue," or erythema of the pharynx; involvement of the peripheral extremities characterized in the early stages by an indurative erythematous rash of palms and soles followed by membranous desquamation; polymorphous nonvesicular truncal exanthem; and acute nonsuppurative enlargement of cervical lymph nodes. An added stipulation is that the illness must not be attributable to a known disease process.
Related Concept Videos
Autoimmune Disorders
Concept and Mechanism of Autoimmune Diseases
The immune system...
Endocarditis II: Clinical Features of Infective Endocarditis
Rheumatic Heart Disease I: Introduction
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
Graves' Disease I: Introduction
Graves Disease II: Pathophysiology

