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Updated: Aug 7, 2026

P50 Sensory Gating in Infants
Published on: December 26, 2013
Latency of brainstem response in children
Insights
This study found sex differences in brainstem electric response latencies in children aged 5-11. While overall male latencies were longer, specific age groups showed varying results, with Wave V latency differences being most pronounced.
Area of Science:
- Neuroscience
- Developmental Psychology
- Audiology
Background:
- Brainstem electric responses are crucial for assessing auditory pathway function.
- Understanding developmental changes in auditory processing is important for identifying potential issues.
- Sex-based differences in neurological development are increasingly recognized.
Purpose of the Study:
- To investigate sex-based differences in brainstem electric response latencies in children.
- To analyze latency variations across different age groups (5-7 and 8-11 years).
- To identify specific waves showing the most significant sex-related latency differences.
Main Methods:
- Collected brainstem electric responses from 70 normal-hearing children (aged 5-11).
- Matched participants by age and sex for comparison.
- Analyzed auditory evoked potential (AEP) latencies, focusing on Wave V.
Main Results:
- Overall, male children exhibited longer latencies than female children.
- No significant latency difference was observed between sexes in the 5-7 year age group.
- A significant latency difference emerged between sexes in the 8-11 year age group.
- Wave V latency demonstrated the most substantial sex-related difference.
Conclusions:
- Sex influences brainstem electric response latencies during middle childhood.
- The emergence of sex differences in auditory processing pathways occurs in later childhood.
- The underlying physical basis for these observed sex differences in latency remains unclear.
Abstract:
Brainstem electric responses were obtained on a group of 70 normal hearing children, aged 5-11 years, matched by age and sex. The recordings were examined for differences in latencies between the sexes at each age. The results showed that males have a longer latency than females, but when broken down into age groups, the latency of children aged 5-7 years was the same, and the latency of children aged 8-11 years differed. The results for latency of wave V of the whole group showed the greatest difference. The reason why such a sex difference should occur in middle childhood is discussed, but no physical cause found.

