Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Reduced active thyroid hormone levels in acute illness

A Burger, P Nicod, P Suter

    Lancet (London, England)
    |March 27, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Growth and Performance of Perovskite Semiconductor CsPbX<sub>3</sub> (X = Cl, Br, I, or Mixed Halide) for Detection and Imaging Applications.

    Materials (Basel, Switzerland)·2024
    Same author

    Genome Wide Conditional Mouse Knockout Resources.

    Drug discovery today. Disease models·2024
    Same author

    A global cloud free pixel- based image composite from Sentinel-2 data.

    Data in brief·2020
    Same author

    15 years of the model study course in medicine at the Ruhr University Bochum.

    GMS journal for medical education·2019
    Same author

    Factors determining microbial colonization of liquid nitrogen storage tanks used for archiving biological samples.

    Applied microbiology and biotechnology·2019
    Same author

    Evaluation of a 3D-printed total knee arthroplasty using radiostereometric analysis: assessment of highly porous biological fixation of the tibial baseplate and metal-backed patellar component.

    The bone & joint journal·2019

    During illness, active thyroid hormones like triiodothyronine (T3) decrease while inactive reverse triiodothyronine (reverse T3) increases. Hormone levels normalize during recovery, maintaining euthyroidism.

    Area of Science:

    • Endocrinology
    • Metabolic studies
    • Thyroid hormone research

    Background:

    • Thyroid hormones regulate metabolism.
    • Disease states can alter thyroid hormone levels and metabolism.

    Purpose of the Study:

    • To investigate changes in thyroid hormone metabolism during acute and subacute illness.
    • To observe the recovery patterns of thyroid hormones post-illness.

    Main Methods:

    • Serum levels of triiodothyronine (T3), tetraiodothyroacetic acid (tetrac), thyroxine (T4), and reverse triiodothyronine (reverse T3) were measured.
    • Thyroid-stimulating hormone (TSH) levels were monitored.

    Main Results:

    • In acute/subacute disease, T3 and tetrac decreased, T4 slightly reduced, and reverse T3 increased, indicating a shift in T4 metabolism.

    Related Experiment Videos

  • During convalescence, T3, tetrac, and T4 levels recovered, and reverse T3 normalized.
  • Thyroid-stimulating hormone levels remained stable, suggesting euthyroidism was maintained.

    • Conclusions:

    • Illness induces a reversible shift in thyroid hormone metabolism towards inactivation.
    • Euthyroid status is maintained despite altered peripheral thyroid hormone levels during illness and recovery.