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Pathophysiological changes associated with Parascaris equorum infection in the foal
Equine Veterinary Journal
|January 1, 1980
Summary
Parascaris equorum infections in foals disrupt gut function and protein metabolism. Infected foals show reduced gut motility and impaired albumin and methionine incorporation, impacting overall health.
Area of Science:
- Veterinary Medicine
- Parasitology
- Equine Health
Background:
- Parascaris equorum is a common intestinal nematode in foals.
- Equine parasitic infections can lead to significant pathophysiological disturbances.
Purpose of the Study:
- To investigate the mechanisms of pathophysiological disturbances caused by mature Parascaris equorum in the equine small intestine.
- To understand the impact of infection on host metabolism and gut function.
Main Methods:
- Radioisotopic techniques were employed to trace metabolic pathways and physiological functions.
- Comparison between infected foals and worm-free control groups.
Main Results:
- Infected foals exhibited reduced gastrointestinal motility compared to controls.
- An increased body solids ratio was observed in infected foals.
- A decreased body pool of albumin and impaired incorporation of dietary methionine into plasma proteins were noted.
Conclusions:
- Parascaris equorum infection significantly alters host physiology and protein metabolism in foals.
- The findings highlight the detrimental effects on gut motility and nutrient utilization, contributing to poor health outcomes.