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Ketamine anesthesia and intraocular pressure

M Antal, G Mucsi, A Faludi

    Annals of Ophthalmology
    |September 1, 1978
    PubMed
    Summary
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    Intramuscular ketamine narcosis significantly increased intraocular pressure in rabbits, despite stable arterial pressure. Other factors likely influenced these pressure changes.

    Area of Science:

    • Ophthalmology
    • Anesthesiology
    • Veterinary Medicine

    Background:

    • Intramuscular ketamine is used for anesthesia.
    • The effect of ketamine narcosis on intraocular pressure (IOP) requires further investigation.

    Purpose of the Study:

    • To investigate the influence of intramuscular ketamine narcosis on intraocular pressure in rabbits.

    Main Methods:

    • Rabbits underwent intramuscular ketamine administration.
    • Tonography and indirect arterial pressure measurements were recorded 5-10 minutes post-administration.

    Main Results:

    • Systolic arterial pressure showed no significant change.
    • Intraocular pressure significantly increased by an average of 7% (maximum 20%).

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  • Arterial and intraocular pressures changed inversely in over half of the cases.

    • Conclusions:

    • Intramuscular ketamine narcosis can elevate intraocular pressure in rabbits.
    • Additional factors beyond arterial pressure influence IOP alterations during ketamine narcosis.