Pathology data quality assurance and data retrieval at the National Center for Toxicological Research

Automated experimental and pathology data collection and reporting systems are utilized at the National Center for Toxicological Research to increase the efficiency of the variety of research studies being performed. In order for the ED01 study to be conducted in an effective manner, usage of these automated systems was considered advantageous due to the study size, approximately 24,000 mice. The large volume of pathology and other experiment data generated in the study required detailed quality assurance and data retrieval, and the use of automated systems allowed this to be performed much more easily than with manual methods. This paper addresses the methods employed to ensure quality and to provide the data retrieval capabilities necessary for conducting and analyzing the ED01 study.