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Paradigms for Pharmacological Characterization of C. elegans Synaptic Transmission Mutants
18:01

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Published on: August 18, 2008

Interaction between phencyclidine (PCP) and GABA-ergic drugs: clinical implications

M K Menon, W G Clark, C Vivonia

    Pharmacology, Biochemistry, and Behavior
    |January 1, 1980
    PubMed
    Summary

    (-) Baclofen effectively antagonized phencyclidine (PCP)-induced hyperactivity in mice, suggesting its potential for managing PCP intoxication. This GABAergic agent also demonstrated anesthetic properties when combined with higher PCP doses.

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