Triangular lunulae. A clue to nail-patella syndrome

Area of Science:

• Dermatology
• Genetics
• Internal Medicine

Background:

• Nail-patella syndrome is a rare genetic disorder affecting multiple body systems.
• Dermatologists can play a role in early diagnosis through physical examination of the nails.

Observation:

• Triangular lunulae (the pale, crescent-shaped base of the nail) are a notable nail finding.
• Other nail abnormalities, such as pitting and ridging, can also be present.

Findings:

• The presence of triangular lunulae and other nail deformities can strongly suggest nail-patella syndrome.
• Differential diagnosis should consider other conditions causing triangular lunulae.

Implications:

• Early identification of nail-patella syndrome through nail examination can lead to timely intervention.
• Increased dermatologist awareness of these nail findings can improve diagnostic rates for this complex syndrome.