[Change in the blood coagulating properties during ergometry in ischemic heart disease]

During ergometric examination of 92 patients with ischemic heart disease and 35 healthy individuals blood coagulation was studied by recording thromboelastograms and electrocoagulograms and determining blood platelet aggregation, fibrinolytic activity and levels of fibrinogen and free heparin in blood. In 65 patients these values in ergometry were determined after treatment with obsidan. It was shown that during physical load there is an intensification of hypercoagulation processes embracing all phases of blood coagulation with simultaneous activation of anticoagulation mechanisms; in contrast to healthy individuals patients with ischemic heart disease are marked by prevalent hypercoagulation. Shifts in the system of blood coagulation depend on the volume of physical load. Heparin and fibrinolytic activity increases up to a certain load level, but when this is surpassed hypercoagulation processes prevail. This may be used as an additional criterion in determining the level of the training regimen in physical rehabilitation of patients.