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Updated: Aug 11, 2026
08:49
A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Malignant melanoma originating from intradermal nevi. A clinicopathologic entity
Archives of Dermatology
|June 1, 1980
Abstract:
Two cases of malignant melanoma arising in preexisting intradermal nevi without a junctional element are described. These cases and the two known to have been reported previously demonstrate similar clinical and morphologic findings. These include an innocuous gross appearance, a nodular growth pattern, and deep levels of invasion. It appears that the origin of the tumor in the dermis conceals malignant transformation. The consequent time lapse and the dermal position of the lesion favor deep penetration of the tumor prior to removal.
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