Primary vesicoureteric reflux in neonates with imperforate anus

Area of Science:

• Pediatric Urology
• Neonatal Surgery
• Diagnostic Imaging

Background:

• Imperforate anus is a congenital condition requiring surgical correction.
• Vesicoureteric reflux is a significant risk in neonates, potentially leading to renal damage.
• Early diagnosis of urinary tract anomalies is crucial for neonatal health.

Purpose of the Study:

• To investigate the incidence and characteristics of primary vesicoureteric reflux in neonates with imperforate anus.
• To determine the relationship between vesicoureteric reflux and the severity of anorectal malformation.
• To assess the utility of cystography in detecting reflux in this patient population.

Main Methods:

• Cystography was performed in 26 neonates with imperforate anus.
• Patient data included sex, presence of urinary tract infections, and intravenous pyelogram findings.
• Reflux severity and its correlation with anorectal anomaly severity were analyzed.

Main Results:

• Primary vesicoureteric reflux was identified in 12 out of 26 neonates (46%).
• Reflux was more prevalent in female infants and those with urinary tract infections.
• Reflux incidence was independent of the anorectal anomaly's severity.
• Reflux was observed in patients with previously undilated upper renal tracts on intravenous pyelogram.

Conclusions:

• Cystography is essential for diagnosing vesicoureteric reflux in neonates with imperforate anus.
• Vesicoureteric reflux is a frequent comorbidity, particularly in females and those with UTIs.
• The presence and severity of reflux are not directly correlated with the anorectal malformation itself.