[Immunomorphology of the lungs in different variants of experimental inflammation]

The results of immunomorphological examinations of the pulmonary tissue of rabbits under conditions of immunisation, intratracheal insertion of capron thread and combinations thereof are described. In all the instances bronchovascular and alveolovascular barriers of the lungs were disturbed leading to the development of alterative, exudative, and proliferative lesions. Inflammatory lesions developed with participation of humoral and cellular immune processes including immunopathologic reactions: immunocomplex damage of the tissue and probably hypersensitivity of the delayed type. The features of the investigated variants of pneumonia are associated with different ways of antigen penetration into the lungs and, evidently, with quantitative and qualitative features of the latter. The role of immunization in the pathogenesis of inflammatory lung diseases consists in the antiinflammatory effect and contribution to the transformation of the acute inflammation into chronic one.