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Updated: Aug 9, 2026

Surgical Placement of Catheters for Long-term Cardiovascular Exercise Testing in Swine
Published on: February 9, 2016
Haemodynamic effects of nicergoline in man at rest and during exercise
Abstract:
1. The intravenous administration of nicergoline (5 mg) was followed by a rapid and sustained lowering of blood pressure; less rapid effects were bradycardia and an elevation of cardiac output. These delayed effects are consistent with an indirect action on the alpha-adrenoreceptors of the central nervous system. 2. Following the oral administration of nicergoline (30 mg), a partial reduction of exercise-induced lactacidaemia was demonstrated, which is consistent with the haemodynamic changes shown at rest.
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