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"Ecdysis" secondary to 5-fluorouracil

H S Yaffee, I Grots

    Cutis
    |June 1, 1980
    PubMed

    Abstract:

    The use of 5-fluorouracil in three patients with basal cell carcinoma was followed by a peculiar necrosis which, when curetted, shelled out completely like a snake skin. We have termed this "ecdysis." Histologic examination revealed tumor necrosis, leukocytes, and fibrin. There have been no recurrences to date.

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