Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Infantile cystoid maculopathy

M T Trese, R Y Foos

    The British Journal of Ophthalmology
    |March 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Bilateral congenital cystoid maculopathy was found in three premature infants, presenting similar macroscopic features to juvenile retinoschisis. Pathological examination revealed retinal ganglion cell loss and central nervous system abnormalities.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Enzyme-induced posterior vitreous detachment in the rat produces increased lens nuclear pO2 levels.

    Experimental eye research·2008
    Same author

    Genetic variants of frizzled-4 gene in familial exudative vitreoretinopathy and advanced retinopathy of prematurity.

    Clinical genetics·2005
    Same author

    West Nile virus chorioretinitis.

    The British journal of ophthalmology·2004
    Same author

    Retinal detachment in focal dermal hypoplasia.

    European journal of ophthalmology·2004
    Same author

    Cosegregation of two unlinked mutant alleles in some cases of autosomal dominant familial exudative vitreoretinopathy.

    European journal of human genetics : EJHG·2003
    Same author

    Factor V Leiden mutation (R506Q) and the risk of advanced retinopathy of prematurity.

    International journal of molecular medicine·2003
    Same journal

    Reference map of multimodal vision deficits in intermediate age-related macular degeneration: contrast sensitivity and low-contrast visual acuity.

    The British journal of ophthalmology·2026
    Same journal

    Commentary on 'identifying patients with poor visual outcomes after primary rhegmatogenous retinal detachment surgery using machine learning'.

    The British journal of ophthalmology·2026
    Same journal

    Automated deep learning-based retinoschisis and detachment volume measurement in pathological myopia with posterior scleral contraction.

    The British journal of ophthalmology·2026
    Same journal

    Bacterial keratitis: a global review of current practices, challenges and innovations.

    The British journal of ophthalmology·2026
    Same journal

    Real-world integration of an autonomous artificial intelligence system for diabetic retinopathy screening in an endocrinology outpatient clinic.

    The British journal of ophthalmology·2026
    Same journal

    Maternal smoking during pregnancy: a risk factor for early childhood ophthalmologic conditions.

    The British journal of ophthalmology·2026
    See all related articles

    Area of Science:

    • Ophthalmology
    • Pathology
    • Neonatal Medicine

    Background:

    • Congenital maculopathy can present with significant visual impairment.
    • Macular lesions in infants are challenging to diagnose, especially when resembling other retinal conditions.
    • Sex-linked juvenile retinoschisis is a known cause of macular changes.

    Purpose of the Study:

    • To report the pathological findings of congenital bilateral cystoid maculopathy in premature infants.
    • To compare these findings with known macular diseases in infants.
    • To highlight the association with central nervous system abnormalities.

    Main Methods:

    • Post-mortem examination of three premature infants.
    • Macroscopic and microscopic analysis of retinal tissues.

    Related Experiment Videos

  • Evaluation of central nervous system (CNS) for abnormalities.

    • Main Results:

    • Bilateral cystoid maculopathy observed in all three infants.
    • Macroscopic appearance of lesions was indistinguishable from sex-linked juvenile retinoschisis.
    • Cystoid changes noted at various retinal levels, with a schisis cavity in the oldest infant.
    • Reduced retinal ganglion cells and CNS abnormalities were present in all cases.

    Conclusions:

    • These are the first reported cases of congenital bilateral cystoid maculopathy.
    • The pathological features of infantile cystoid macular lesions are described.
    • Congenital cystoid maculopathy may be associated with CNS abnormalities and ganglion cell loss.