Related Experiment Video
Updated: Aug 10, 2026

Investigations on the Ga(III) Complex of EOB-DTPA and Its 68Ga Radiolabeled Analogue
Published on: August 17, 2016
Phlogistic properties of the serum proteins, albumin and transferrin
Abstract:
In the experimental model for inflammation, footpad edema induced by injections of monosodium urate crystals, effects of two acute-phase reactants, the carrier proteins albumin and transferrin, were studied. Addition of small amounts of these serum components to the test system resulted in greater swelling. A dose-related response was demonstrated. Doubling the amount of transferrin produced increased inflammation. Comments are presented on the possible protective role of pertubations in the serum proteins classified as acute-phase reactants in the organism's response to tissue injury or inflammation.
Related Concept Videos
Globular and Fibrous Proteins
Globular proteins are also known as spheroproteins and typically are approximately round in shape. They contain a mix of amino acid types and contain differing sequences in their primary structures. Globular proteins have many different functions, such as enzymes, cellular messengers, and molecular transporters. These roles often require the proteins to be...
Globular Proteins
Globular proteins serve many important physiological functions, such as acting as enzymes, cellular messengers, and molecular transporters. These roles often require the proteins to be soluble in the aqueous...
Drug Distribution: Plasma Protein Binding
Composition of Blood Plasma
Drug Binding to Blood Components
HSA is the most abundant plasma protein and is vital in drug binding. It contains distinct drug-binding sites, with different drugs exhibiting affinity for specific sites. There are three main drug-binding domains for HSA: sites I, II, and III. These domains are further...
Hepatic Drug Clearance: Effect of Protein Binding
For low-extraction-ratio drugs that are less than 80% protein-bound, minor changes in protein binding...

