Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Proliferative glomerulonephropathy in multiple myeloma

F G Silva, A Meyrier, L Morel-Maroger

    The Journal of Pathology
    |April 1, 1980
    PubMed
    Summary

    This study details a multiple myeloma case with unique kidney damage, highlighting light chain proteins

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Correction: Exchange-bias and magnetic anisotropy fields in core-shell ferrite nanoparticles.

    Scientific reports·2025
    Same author

    Serum and saliva immunoglobulin (immunoglobulin G, immunoglobulin A, and immunoglobulin M) dynamics in newborn calves and their association with health status during the first week of life: An exploratory study.

    Journal of dairy science·2025
    Same author

    Interactions between pea protein and gellan gum for the development of plant-based structures.

    International journal of biological macromolecules·2023
    Same author

    Exchange-bias and magnetic anisotropy fields in core-shell ferrite nanoparticles.

    Scientific reports·2021
    Same author

    Chemical composition and biological activities of essential oil from flowers of Psidium guajava (Myrtaceae).

    Brazilian journal of biology = Revista brasleira de biologia·2020
    Same author

    Biological control in the germination of seeds from two species native of the Cerrado region.

    Brazilian journal of biology = Revista brasleira de biologia·2020

    Area of Science:

    • Nephrology
    • Oncology
    • Pathology

    Background:

    • Multiple myeloma (MM) is a plasma cell malignancy.
    • Renal involvement is common in MM, often due to cast nephropathy.
    • Unusual renal manifestations can occur, necessitating detailed investigation.

    Observation:

    • A unique case of MM presented with both intra- and extracapillary proliferative glomerulonephritis.
    • The patient exhibited other atypical morphologic and clinical features.
    • Light chain proteins were suspected as a key factor in the glomerular pathology.

    Findings:

    • The described glomerulonephritis represents an uncommon renal complication of multiple myeloma.
    • Analysis suggests a significant role for monoclonal light chain proteins in the development of glomerular lesions.
    • Therapeutic interventions demonstrated positive effects on the renal lesions' activity and progression.

    Implications:

    • This case expands the understanding of renal manifestations in multiple myeloma.
    • It underscores the pathogenic role of light chain proteins in diverse glomerular diseases.
    • Effective treatment of the underlying myeloma can positively impact renal outcomes.

    Related Experiment Videos