Is it worthwhile to treat Peyronie disease?

Several articles describing the natural history of Peyronie disease have shown that untreated patients seem to have spontaneous improvement. It has been suggested that this could be the reason for the success of so many different methods. A review of the literature and of our previous experience has been done, trying to clarifying this issue. Our findings indicate that although treatment does not increase appreciably the percentages of amelioration of symptoms over the spontaneous evolution, it accelerates the improvement. Analysis is made of several factors which we have found to be important when making a decision for treatment: type of symptoms, psychologic impact of them, possible complications of the different therapy methods, and time interval from beginning of symptoms to treatment. The question of the worthiness of treating Peyronie disease does not have a single answer. We believe there are definite indications and several factors to be considered.