[Inhibition of the autotrophic growth of hydrogen bacteria by the autoregulation factor]

The purpose of this work was to study the action of the autoregulation factor isolated from the organotrophous culture of Pseudomonas carboxydoflava Z-1107 on autotrophous growth of this organism and some other cultures of hydrogen bacteria. If a sufficient dose of this metabolite was added to the culture growing lithoautotrophously, the growth of Ps. carboxydoflava Z-1107 stopped completely after 24 hours. A curve of false diauxia was observed if an increase in the concentration of the autoregulation factor in the culture was not great enough. When the factor acted on the autotrophously growing cultures of Alcaligenes eutrophus, Pseudomonas pantotropha and Paracoccus denitrificans, it was established that this endogenous metabolite possessed group specificity, and was capable of inhibiting, more or less, autotrophous growth of this hydrogen bacterium.