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Perianal Crohn's disease

J Alexander-Williams, P Buchmann

    World Journal of Surgery
    |January 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Crohn's disease often presents with perianal fissures and fistulas, which frequently heal or remain asymptomatic over time. A conservative management approach is recommended for these common Crohn's disease manifestations.

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    Area of Science:

    • Gastroenterology
    • Colorectal Surgery

    Background:

    • Perianal disease is a common manifestation of Crohn's disease.
    • Lesions may be asymptomatic for extended periods.

    Purpose of the Study:

    • To evaluate the long-term outcomes of perianal fissures and fistulas in Crohn's disease patients.
    • To assess the efficacy of a conservative management policy.

    Main Methods:

    • A 10-year follow-up of 109 patients with perianal Crohn's disease.
    • Extensive investigation including sigmoidoscopy, biopsy, and manometry in 61 patients.

    Main Results:

    • Many fissures and most fistulas healed during the follow-up period.
    • Some cases progressed to asymptomatic anal stenosis.

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  • A small proportion required rectal excision, primarily for reasons other than perianal disease.

    • Conclusions:

    • A conservative management strategy is often effective for perianal Crohn's disease.
    • Long-term outcomes are generally favorable, with a high rate of healing and asymptomatic progression.