Related Experiment Video
Updated: Jul 25, 2026

The Perinatal Asphyxiated Lamb Model: A Model for Newborn Resuscitation
Published on: August 15, 2018
[Complications of resuscitation and intensive therapy in infants (proceedings)]
Insights
Infusion therapy complications in children, like thrombosis and thrombophlebitis, can lead to sepsis and organ damage. Premature newborns face risks from artificial pulmonary ventilation due to immature lung tissue.
Area of Science:
- Pediatrics
- Neonatology
- Medical Complications
Context:
- Infusion therapy is a common medical intervention in pediatric care.
- Complications such as thrombosis and thrombophlebitis are frequently observed.
- Neonates, especially premature infants, are particularly vulnerable to iatrogenic complications.
Purpose:
- To highlight the common complications associated with infusion therapy in children.
- To discuss the causes and consequences of umbilical and subclavian vein thrombophlebitis.
- To examine the risks of artificial pulmonary ventilation in premature newborns.
Summary:
- The most common infusion therapy complications in children are thrombosis and thrombophlebitis of the umbilical and subclavian veins.
- Umbilical vein thrombophlebitis, often from exogenous infection, can cause umbilical sepsis. Subclavian vein thrombophlebitis in nurslings frequently stems from endogenous infection.
- Infancy's immature physiology exacerbates tissue hyperhydration and cellular damage (liver, kidneys). Artificial pulmonary ventilation in premature infants risks lung injury (emphysema, pneumothorax) and may be ineffective due to lung immaturity.
Impact:
- Understanding these complications is crucial for preventing serious infant morbidity and mortality.
- This information aids clinicians in managing infusion therapy and mechanical ventilation in vulnerable pediatric populations.
- Highlights the need for careful monitoring and tailored interventions in neonatal intensive care units.
Abstract:
Most frequent complications of infusion therapy in children include thrombosis and thrombophlebitis of the umbilical and subclavian veins. In the perinatal period thrombophlebitis of the umbilical vein is due to exogenous infection and becomes the source of umbilical sepsis. Thrombophlebitis of the subclavian vein in nurslings results more frequently from endogenous infection. Because of morpho-functional immaturity in infancy, hyperhydration of tissues is extreme, with vacuolar dystrophy of cells up to their necrosis, particularly in the liver and kidneys. Artificial pulmonary ventilation (APV), particularly in premature newborns, is frequently accompanied by breaks of alveolar septae, development of bullous and interstitial emphysema, pneumothorax. In deeply premature infants APV may be ineffective because of immaturity of the lung tissue.
Related Concept Videos
Acute Respiratory Failure-III
Acute Respiratory Failure-IV
Acute Respiratory Failure-V
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Endoscopic Studies II: Thoracocentesis
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
Cardiopulmonary Resuscitation I: Adult
Cardiopulmonary Resuscitation IV: Pharmacological Management

