[Effect of methazolamide on the intraocular pressure of patients with open-angle glaucoma (author's transl)]

The ocular hypotensive effects of different oral doses of methazolamide, a carbonic anhydrase inhibitor with similar properties to acetazolamide, were compared in a double-blind trial with 11 patients with glaucoma. In low doses methazolamide offers the possibility of treating glaucoma without side effects or acidosis, but acetazolamide remains the oral medication of choice for glaucoma, because it lowers intraocular pressure more effectively than methazolamide.